Intravenous antibiotics and Pseudomonas aeruginosa

We believe that prompt initiation of eradication protocols for new Pseudomonas aeruginosa infection and early, high dose intravenous antibiotic treatment of respiratory exacerbations have been the most important factors responsible for the improved outlook for people with CF (Conway et al, 1985; Smith et al, 1988; Regelmann et al, 1990; Bradley et al, 1999). All patients require regular respiratory cultures (throat/cough swabs or sputum) and appropriate antibiotic treatment to eradicate any pathogenic bacteria (Cystic Fibrosis Trust, 2002).